OpenTrials was designed as a multilingual 'open source' application suitable to any country or region willing to operate a clinical trials registry. In Latin America and the Caribbean, national and regional instances of this platform are under consideration, under the supervision of PAHO/WHO.

OpenTrials instances will be capable of interoperating with other registries, allowing the exchange of records following the standards set by the International Clinical Trials Registry Platform of the World Health Organization (ICTRP/WHO).