authentication of human cell lines

Mainstays of biomedical research, permanent lines of cloned cells are used to study the biology of health and disease and to test prospective medical therapies. Yet, all too often, these apparent pillars of bioscience and biotechnology crumble because they are crafted from faulty starting materials: misidentified or cross-contaminated cell lines. Writing in the June 2016 issue of PLOS Biology, scientists from the National Institute of Standards and Technology (NIST) call for "community action" to assemble a "comprehensive toolkit for assuring the quality of cell lines," employed at the start of every study.