Hierarchical Editing Language for Macromolecules (HELM)
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Bio-IT World Announces the Winners of Its Tenth Annual Best Practices Awards
Bio-IT World announced the winners of its tenth annual Best Practices Awards competition this morning in a plenary session at the 2014 Bio-IT World Conference & Expo in Boston. Grand prize winners were named in five life sciences categories highlighting best practices in clinical trial IT, research infrastructure, bioinformatics, cloud computing and data management from AstraZeneca and Tessella, U-BIOPRED, the Pistoia Alliance, Baylor College of Medicine, and Genentech. Read More »
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European Bioinformatics Institute (EMBL-EBI) ChEMBL 20 incorporates the Pistoia Alliance’s HELM annotation
The European Bioinformatics Institute (EMBL-EBI) has released version 20 of ChEMBL, the database of compound bioactivity data and drug targets. ChEMBL now incorporates the Hierarchical Editing Language for Macromolecules (HELM), the macromolecular representation standard recently released by the Pistoia Alliance.
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Pfizer Shares Software For Biotech Drug Research With Pharma Rivals
Pfizer ($PFE) has led the way in an effort to share software and standards for managing data on complex molecules, providing the tech know-how on a precompetitive basis to competitors such as GlaxoSmithKline ($GSK), Roche ($RHHBY) and Bristol-Myers Squibb ($BMY). Read More »
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Pistoia Alliance Driving Open Innovation in Bioresearch
The Pistoia Alliance recently held its 4th Annual Conference at the Marriott Marquis in New York City. As part of the Next Chapter Initiative this was widened to a three-day event to include a special members-only meeting on the second day, kindly hosted by Thomson Reuters at their headquarters in Times Square, and a face-to-face board meeting hosted by Roche at the Alexandria Centre. Read More »
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Pistoia Alliance Launches New Chemical Safety Library Project
The Pistoia Alliance...has started work on the Chemical Safety Library, a project which will allow for the capture and sharing of previously inaccessible reaction incident information to enhance laboratory safety...The Chemical Safety Library will see the creation of an informatics driven resource to allow all organizations to effectively share chemistry-related incident reports, delivering value from real life incidents and learnings. The data will be collected in a publicly available central resource and rule sets and triggers will be created that can be tied to scientists’ reaction planning tools, so that if an organization should attempt to repeat a procedure that previously resulted in an accident, a warning will be issued.
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Pistoia Alliance Launches New Map of Alliances project
The Pistoia Alliance, a global, not-for-profit alliance of life science organizations that work together to lower barriers to innovation in R&D, has started a new project called Map of Alliances. The Map of Alliances project will catalogue the various life sciences consortia, partnerships, foundations and alliances in the life sciences sector and investigate how these collaborative efforts form an interconnected web of partnerships. The Map of Alliances project will see the Pistoia Alliance develop a comprehensive picture of how all these alliances, including those that involve commercial, not for profit and academic partners, are connected across the life sciences sector.
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Pistoia Alliance Wins Bio-IT World Grand Prize-Continues Innovation Mission
I received an email newsletter this morning from the Pistoia Alliance and it was so full of information and updates that I decided to post the entire newsletter as an article. A note on the Pistoia Alliance is long overdue. I had meant to write an article on the Alliance back in April after the 2014 Bio-IT World conference organizers announced that Pistoia's HELM project had been chosen as one of the Grand prize winners. Read More »
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The Pistoia Alliance Releases Exchangeable HELM
The Pistoia Alliance and quattro research are pleased to announce the release of an extension to the HELM biomolecular representation standard. HELM (Hierarchical Editing Language for Macromolecules) enables the representation of a wide range of biomolecules (e.g. proteins, nucleotides, antibody drug conjugates) whose size and complexity render existing small-molecule and sequence-based informatics methodologies impractical or unusable.
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Universal Language: The Pistoia Alliance Takes on Indescribable Biology
Best Practices WinnerThe Pistoia Alliance has previously sponsored new methods for querying databases and the scientific literature, and a more effective algorithm for compressing and sharing genetic sequencing data. Over the past year, another Pistoia project, HELM, has entered the public domain after gradual development by an assortment of Alliance members. An open source language and set of editing tools for working with large biomolecules, HELM has already become a foundational part of research in at least three large pharmaceutical companies. Read More »
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