National Institutes of Health (NIH)
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Policy: NIH Plans to Enhance Reproducibility of Biomedical Research
In a recent editorial in the journal Nature, Francis Collins and Lawrence Tabak from the National Institutes of Health (NIH) discuss the concerns that NIH has with current lack of reproducibility in biomedical research, and propose steps for improving the repoducibility records. In their editorial they point out that we have traditionally considered science to be a self-correcting field. Given the expectation that over time, all reported works would be replicated by peers. Read More »
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Precision Medicine Requires Unlocking Data from EHRs, Other Sources
Venture Funding for Digital Health in 2015 Reaches 2014 Level
Health information technology is “foundational” to President Obama’s $215 million Precision Medicine Initiative aimed at treating the specific needs and characteristics of individual patients, according to Karen DeSalvo, M.D., national coordinator for HIT. Read More »
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Precision Medicine, Blue Button Among White House Big Data Efforts
Precision medicine, medical research, and improved patient engagement through initiatives like Blue Button are among the highlight achievements of the Obama Administration’s emphasis on data transparency and information sharing, says a White House fact sheet celebrating the nation’s big data progress. The following is a rundown of some of the specific open-data health efforts of the Obama Administration...
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Precision Medicine: Analytics, Data Science and EHRs in the New Age
The promise of genomics and personalized care are closer than many realize. But clinical systems and EHRs are not ready yet. While policymakers and innovators play catch-up, here’s a look at what you need to know. Considering how fast technology advances in the healthcare industry, it seems natural that a once-innovative concept could become obsolete in the span of, say, a dozen years. Knowledge, comprehension and capabilities continue moving forward, and if the instruments of support don't keep pace, it can cause a rift to appear. If nothing is done, it can exacerbate into a seismic event...
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Prometheus Research Announces $1M in Expanded Funding From Public and Private Sectors, Sees Broader Applications for Their Integrated Registry Platform
Prometheus Research announced today they have received nearly $1M in additional support from the National Institutes of Health (NIH) and health-focused private philanthropies for their work developing open-source integrated registry software and related clinical research informatics data standards. Building on the success of their Phase I SBIR award from the National Institute of Mental Health (NIMH), two new NIH awards provide significant additional funding for enhancing Prometheus' Research Exchange Database (RexDB®) platform with features required in interventional research.
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Prometheus Research Awarded $700,000 NIH SBIR Grant To Improve Open Source Tools For Autism Research
Prometheus Research, an integrated data management services provider, announced today that it has been awarded $700,000 by the National Institutes of Health (NIH) Small Business Innovation Research (SBIR) program to extend its Open Source Research Exchange Database (RexDB) for the management of autism spectrum disorders research. Read More »
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Publishers Flip Out, Call Bill To Provide Open Access To Federally Funded Works A 'Boondoggle'
A year ago, we wrote about Rep. Mike Doyle introducing an important bill to provide public access to publicly funded research. [...] Unlike just about any other publication, [academic] journals don't pay their writers (and in many subject areas, authors need to pay to submit), they don't pay the peer reviewers -- and then they charge positively insane amounts to university libraries... Read More »
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ReWalk Featured in VA National Multi-Center Clinical Exoskeleton Trial
ReWalk Robotics Ltd...announced that the Department of Veterans Affairs ("VA") has publicly listed details of a national, multi-center study utilizing the Company's Personal 6.0 Exoskeleton Systems. The VA released full details of the study titled, "Exoskeleton Assisted-Walking in Persons With SCI: Impact on Quality of Life" on the clinical trials section of the National Institutes of Health (NIH) website (www.clinicaltrials.gov Identifier: NCT02658656). Several key components of the study outlined by the VA, include...
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Rice U. Lab Creates Open-Source Optogenetics Hardware, Software
Nobody likes a cheater, but Rice University bioengineering graduate student Karl Gerhardt wants people to copy his answers. That’s the whole point. Gerhardt and Rice colleagues have created the first low-cost, easy-to-use optogenetics hardware platform that biologists who have little or no training in engineering or software design can use to incorporate optogenetics testing in their labs. Rice’s Light Plate Apparatus (LPA) is described in a paper available for free online this week in the open-access journal Scientific Reports...
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Sage Bionetworks Advocates for Open Systems in Health Research
Sage Bionetworks, a nonprofit biomedical research organization, continues its work to redefine the way in which health data is gathered, shared and used through the use of open systems, incentives and norms. In a Nature commentary published today, a set of governing principles for digital health data analysis that are designed to maximize the contribution of large-scale digital data to advancing medical care are described. This commentary was co-authored by John Wilbanks, Chief Commons Officer at Sage Bionetworks and Eric Topol, MD, Director of the Scripps Translational Science Institute, and Chief Academic Officer of Scripps Health. The two work together on the NIH-funded Precision Medicine Initiative that was announced earlier this month.
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Scientific Publishers Offer Solution To White House's Public Access Mandate
A group of scientific publishers today announced a plan for allowing the public to read taxpayer-funded research papers for free by linking to journals' own websites... Read More »
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Scientists Develop ‘Lab on a Chip’ That Costs 1 Cent to Make
Researchers at the Stanford University School of Medicine have developed a way to produce a cheap and reusable diagnostic “lab on a chip” with the help of an ordinary inkjet printer. At a production cost of as little as 1 cent per chip, the new technology could usher in a medical diagnostics revolution like the kind brought on by low-cost genome sequencing, said Ron Davis, PhD, professor of biochemistry and of genetics and director of the Stanford Genome Technology Center...
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Scientists Scour the Globe for a Drug to Kill Deadly Brain-Eating Amoeba
The deaths hit the headlines every summer, sometimes five or six of them across the country. They’re newsworthy for their rarity and for how innocuous the events leading up to them are — it’s usually a young person who was swimming in a lake, got some water up their nose, and within days, was dead. The cause is an amoeba called Naegleria fowleri, which when it infects the brain, causes massive swelling that is almost always fatal. Over the past half-decade, 137 people in the US have died of the infection...
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Shutdown Imperils Costly Lab Mice, Years Of Research
The government shutdown is likely to mean an early death for thousands of mice used in research on diseases such as diabetes, cancer and Alzheimer's. Read More »
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Six Funders Working To Set Science Free
Sharing information is easier than ever, but much scientific research remains maddeningly walled-off in publications charging thousands of dollars for access. Some prominent funders are part of a growing movement to make science more open...
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