clinical trials

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Research Symbiosis Makes Mathematical Crystal Ball to Gaze into Future of Prostate Cancer Treatment

Press Release | University of Colorado Cancer Center | August 4, 2017

The chemotherapy docetaxel is widely accepted as a standard therapy for metastatic castration-resistant prostate cancer. But 10-20 percent of patients will have adverse side effects that force discontinuation of treatment. These patients may have been better off with another treatment in the first place, but who’s to know before trying the drug which patients will go on to experience debilitating side effects? A crowdsourced competition asked this as an open question. Today in the Journal of Clinical Oncology Clinical Cancer Informatics, competition organizers and participating teams report their findings...

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Researcher with Stage 4 Cancer Launches Site to Help Others Navigate Clinical Trials

Bob Tedeschi | STAT | May 17, 2017

Among patients with colon cancer, researcher Tom Marsilje has made a name for himself by helping others learn about new clinical trials. He has scoured the database ClinicalTrials.gov, circulated a weekly spreadsheet, and served as a clearinghouse for patients desperate for a chance to beat back their disease. But, for Marsilje, it has been a labor-intensive process, and it has been hard to escape a troubling reality...

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Rethinking Fat: The Case For Adding Some Into Your Diet

Allison Aubrey | The Salt | March 31, 2014

Remember the fat-free boom that swept the country in the 1990s? Yes, we know from the Salt readers who took our informal survey that lots of you tried to follow it. And gave up. Read More »

ReWalk Featured in VA National Multi-Center Clinical Exoskeleton Trial

Press Release | ReWalk Robotics | February 3, 2016

ReWalk Robotics Ltd...announced that the Department of Veterans Affairs ("VA") has publicly listed details of a national, multi-center study utilizing the Company's Personal 6.0 Exoskeleton Systems. The VA released full details of the study titled, "Exoskeleton Assisted-Walking in Persons With SCI: Impact on Quality of Life" on the clinical trials section of the National Institutes of Health (NIH) website (www.clinicaltrials.gov Identifier: NCT02658656). Several key components of the study outlined by the VA, include...

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Sequenom Chose Open Source EDC System ClinCapture For Cost Efficiency And Team Commitment

Press Release | Clinovo, Sequenom | November 27, 2013

San Diego-Based Medical Device Company Sequenom Highlights Cost Savings and Team Responsiveness Using ClinCapture, Clinovo’s Open Source Electronic Data Capture (EDC) System Read More »

Significant Distortions Discovered in Leading Genetics Study Method - Open Source Software can Detect and Correct Them

Press Release | Icahn School of Medicine at Mount Sinai | April 24, 2018

Many conclusions drawn from a common approach to the study of human genetics could be distorted because of a previously overlooked phenomenon, according to researchers at the Department of Genetics and Genomics Sciences at the Icahn School of Medicine at Mount Sinai and collaborators from Massachusetts General Hospital and the Broad Institute. Their conclusions and a unique method they developed to help correct for this distortion were recently published in Nature Genetics.

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Simulators Help Build A Better Drug Trial

Jonathan D. Rockoff | Wall Street Journal | November 17, 2013

Researchers have started using powerful computer simulators to design better drug trials and help bring new medicines to market with fewer failures. Read More »

SMART On The Agenda At AMIA 2012

Staff Writer | SMART Platforms | November 3, 2012

The AMIA 2012 Annual Symposium begins today in Chicago, where it is currently “Informatics Week” as declared by Mayor Rahm Emanuel. Read More »

Sneak Peek: What The White House Is Thinking About Antibiotic Resistance

Maryn McKenna | Wired | April 4, 2014

The President’s Council of Advisors on Science and Technology (PCAST for short) is preparing a major report on the problem of antibiotic resistance. The report won’t be published for a few months, but today PCAST held one of its periodic meetings, and aired what it thinks the most important issues are going to be. [...] Read More »

Study Unveils New Way to Starve Tumors to Death

Press Release | Washington University School of Medicine in St. Louis | January 24, 2017

For decades, scientists have tried to halt cancer by blocking nutrients from reaching tumor cells, in essence starving tumor cells of the fuel needed to grow and proliferate. Such attempts often have disappointed because cancer cells are nimble, relying on numerous backup routes to continue growing. Now, scientists at Washington University School of Medicine in St. Louis have exploited a common weak point in cancer cell metabolism, forcing tumor cells to reveal the backup fuel supply routes they rely on when this weak point is compromised. Mapping these secondary routes, the researchers also identified drugs that block them. They now are planning a small clinical trial in cancer patients to evaluate this treatment strategy...

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Sunday Shutdown Reader: Harold Varmus On Self-Destruction In The Sciences

James Fallows | Atlantic | October 13, 2013

"Now that the shutdown is nearing the end of its second week, further consequences are coming into view ..." Read More »

Tasly Pharmaceuticals To Use OpenClinica Enterprise For TCM Clinical Trial Data Management

Press Release | Tasly, OpenClinica | April 4, 2014

OpenClinica, LLC announces that Tasly Pharmaceuticals Inc. has selected the OpenClinica Enterprise Edition for clinical trial electronic data capture (EDC) and clinical data management. Tasly Pharmaceuticals is a research-driven group invested in the development and distribution of modern TCM (Traditional Chinese
Medicine) throughout key markets across Southeast Asia, Europe, North America and Africa.

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Telemedicine in Clinical Trials Highlighted At Upcoming Conferences

Press Release | AMC Health | September 9, 2014

...At the Mobile and Clinical Trials Conference on September 10 and the  4th annual Dpharm: Disruptive Innovations in Clinical Trials Conference September 11-12, panelists will describe how telemedicine technology from AMC Health, a pioneer in providing telemedicine solutions for clinical trials, is being used to overcome these limitations...

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The 5 Essentials of Cloud Computing For Clinical Trials

The pharmaceutical industry has been historically slow in adopting new technologies and it is only now that we are beginning to see the emergence of cloud based eClinical systems for the clinical trial industry. This article explores the true definition of cloud computing as defined by the National Institute of Standards and Technology (NIST) and applies it to eClinical systems. Read More »

The Collateral Benefits of India's Open Source Drug Discovery Programme

Priyanka Pulla | Forbes India | April 9, 2014

India's Open Source Drug Discovery programme is struggling for lack of expertise and a research ecosystem. However, the programme's real contribution may be the creation of just such an ecosystem Read More »