drug discovery
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GSK Expands Open-Source Research Project In TB
GlaxoSmithKline (GSK) has screened its entire pharmaceutical compound library of more two million compounds and identified about 200 hits with potential against tuberculosis (TB), which it will make available to external research teams as part of its drive towards an 'open innovation' approach to R&D. Read More »
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Heart Failure Breakthrough May Come From "Open Source" Cancer Drug Development: Discoveries
A newly-discovered cancer drug may be a breakthrough in treating heart failure, thanks to a groundbreaking “open source” approach to drug discovery that allowed a Case Western Reserve University heart specialist free access to the compound for his research. Read More »
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HIMSS16: Cloudera Demos Open Source Precision Medicine and Healthcare Enterprise Data Hub
As the Healthcare Information and Management Systems Society (HIMSS) 2016 theme implies -- “transforming health through IT” -- healthcare organizations are increasingly focused on taking advantage of big data to personalize the patient experience and improve clinical outcomes. Cloudera’s commitment to this effort was exemplified this morning, when the company annunced its contributions to President Obama’s Precision Medicine Initiative (PMI). By implementing Cloudera Enterprise, healthcare organizations are better equipped to deliver precision medicine with a modern data platform that facilitates information sharing across silos while remaining HIPAA-compliant...
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Indian Pharma Industry Should Work For Inventing New Drugs, Dr Abdul Kalam
The Indian pharmaceutical industry should turn their attention to invent new drugs from molecule levels and each manufacturing unit should try to become invention centres, opined Dr APJ Abdul Kalam, former President of India. Read More »
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Japanese Drugmakers Open 'Libraries' In $100 Million Health Project
Five top Japanese drug companies are to open their "libraries" of experimental compounds to scrutiny by scientists hunting new treatments for malaria, tuberculosis and other diseases affecting the world's poor. Read More »
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Join The Movement : Open Source Drug Discovery
OSDD or Open Source Drug Discovery is a community of students, scientists, researchers, academicians, institutions, corporations and anyone who is committed to discovery of drugs in an open source mode. [...] Read More »
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Medicines for Malaria Venture and EMBL-EBI Establish One-stop Shop for Malaria Drug Data
ChEMBL, the online drug-discovery database based at EMBL-EBI, now makes it easy to access all data pertaining to compounds from MMV’s open-access Malaria Box and other open-source malaria research initiatives. Read More »
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Merger of TranSmart, i2b2 Aims to Provide Informatics Boost to Precision Medicine Efforts
As genomic tools continue to make their way from the research lab into clinical practice, the recently announced merger between the TranSmart Foundation and the Informatics for Integrating Biology and the Bedside (i2b2) aims to provide researchers and clinicians with an open-source resource that could benefit precision medicine efforts. Earlier this month, the two organizations announced their plans to combine into a single foundation focused on providing open-source biomedical software and databases for precision medicine...
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New Drugs Trail Many Old Ones In Effectiveness Against Disease
Despite the more than $50 billion that U.S. pharmaceutical companies have spent every year since the mid-2000s to discover new medications, drugmakers have barely improved on old standbys developed decades ago. Read More »
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Open Access Initiative Reveals Drug Hits For Deadly Neglected Tropical Diseases
The Drugs for Neglected Diseases initiative (DNDi) and Medicines for Malaria Venture (MMV) announce today the identification of three chemical series targeting the treatment of deadly neglected tropical diseases (NTDs), through DNDi’s screening of MMV’s open access Malaria Box. Read More »
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Open Data Key To Tackling Neglected Tropical Diseases
Open data access could promote collaborations among researchers in Africa and help in the fight against malaria, tuberculosis (TB) and neglected tropical diseases such as sleeping sickness, also called African trypanosomiasis. At a time when demand for open data in health and drug discovery is dominating the digital space, some researchers say the model could work for Africa and alleviate the sufferings of many from these diseases. Following the call on 23 April this year from the WHO for the disclosure of all results from clinical trials of new medicines, there is a push towards greater transparency.
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Open PHACTS: Semantic Technologies And Drug Discovery
Research and discovery in the life sciences is a pretty complicated business. The complexity of the modern scientific process seems to be a reflection of the intricacies of life and the processes associated with disease and its treatment. Furthermore, as technologies become more advanced, so too does the problem of managing the ever expanding quantity of data being generated. Read More »
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Open Source Drug Discovery Gathers Steam
The unique CSIR initiative, now has over 6,000 registered participants working on an open source platform for the discovery of drugs of diseases such as TB, malaria and more. Read More »
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Open Source Paradigm Could Swipe Biz From CROs: Beroe
However “open source” drug discovery – by which a contractor buys a compound with little data, shares that data with a sponsor and then provides development services for a fee – could be a way to plug the gaps, Pakaravoor told us.
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Open Source Projects Are Transforming Machine Learning and AI
Machine learning and artificial intelligence have quickly gained traction with the public through applications such as Apple’s Siri and Microsoft’s Cortana. The true promise of these disciplines, though, extends far beyond simple speech recognition performed on our smartphones. New, open source tools are arriving that can run on affordable hardware and allow individuals and small organizations to perform prodigious data crunching and predictive tasks.
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