SARS-CoV-2

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Approval Of A Coronavirus Vaccine Would Be Just The Beginning - Huge Production Challenges Could Cause Long Delays

The race for a SARS-CoV-2 vaccine is well underway. It's tempting to assume that once the first vaccine is approved for human use, all the problems of this pandemic will be immediately solved. Unfortunately, that is not exactly the case. Developing a new vaccine is only the first part of the complex journey that's supposed to end with a return to some sort of normal life. Producing hundreds of millions of vaccines for the U.S. - and billions for the world as a whole - will be no small feat. There are many technical and economic challenges that will need to be overcome somehow to produce millions of vaccines as fast as possible.

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Data Management for Large-scale COVID-19 Immunization: This is all not as simple as it seems

There is a global race for the development of a vaccine for the SARS-CoV-2 virus that causes COVID-19. Finding a vaccine that works and receives approval is only part of the process. There are a series of other steps that need to be taken so that the vaccine can be delivered. These include the mass production of the vaccine, shipment, administration and record-keeping. This may be even more complex as there may be several vaccines. In this article we review some of these issues with a particular focus on the United States.

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How Laboratories and their Systems can Weather Natural Disasters and Pandemics

We are currently experiencing a global pandemic - which, while perhaps included in disaster preparedness Standard Operating Procedures (SOPs) by many labs as a possible disaster, still has caught most the infrastructure and health systems of most nations largely unprepared, and is causing major disruption because it was arguably not seen as one of the most likely events. Disaster preparedness has typically tended to focus on IT and data management risks and/or natural disasters. SOPs center around standard, daily lab safety. The truth is that whatever the odds of a particular disaster, they become 100% once they happen. It's important to have sufficient risk-reduction SOPs in play, and a good Continuity Of Operations Plan (COOP) for each potential scenario to ensure the best chance of coping during the event and recovering afterwards.

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University of Chicago Awarded $20 Million To Host COVID-19 Medical Imaging Center

Press Release | University of Chicago | August 7, 2020

A new center hosted at the University of Chicago-co-led by the largest medical imaging professional organizations in the country-will help tackle the ongoing COVID-19 pandemic by curating a massive database of medical images to help better understand and treat the disease. Led by Prof. Maryellen Giger of UChicago Medicine, the Medical Imaging and Data Resource Center (MIDRC) will create an open-source database with medical images from thousands of COVID-19 patients. The center will be funded by a two-year, $20 million contract from the National Institute of Biomedical Imaging and Bioengineering at the National Institutes of Health (NIH).

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White House Call to Action to the Tech Community on New Open Access Machine Readable COVID-19 Dataset

Press Release | White House | March 16, 2020

Today, researchers and leaders from the Allen Institute for AI, Chan Zuckerberg Initiative (CZI), Georgetown University's Center for Security and Emerging Technology (CSET), Microsoft, and the National Library of Medicine (NLM) at the National Institutes of Health released the COVID-19 Open Research Dataset (CORD-19) of scholarly literature about COVID-19, SARS-CoV-2, and the Coronavirus group. Requested by The White House Office of Science and Technology Policy, the dataset represents the most extensive machine-readable Coronavirus literature collection available for data and text mining to date, with over 29,000 articles, more than 13,000 of which have full text.

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